What supports this
Match the claim to the right kind of proof
A strong claim points to a named product, a group of people and a result that was actually measured. The closer the match, the more useful the evidence.
Start with the product record
For an approved medicine, begin with the Food and Drug Administration, or FDA, product record and current label. The label is the full FDA document online for that product; together, the two records show the exact product and approved use.
For a compounded medicine, there is no FDA approval review of the finished product before it is marketed.
- Exact ingredient and brand
- People included in the study
- Result that was measured
- Length of the study
- Who paid for the study
What the main weight trials found
A study called STEP 1 included 1,961 adults without diabetes. Those who received weekly semaglutide lost about 15% of body weight over 68 weeks; the group on a dummy shot lost about 2%.
A study called SURMOUNT-1 included 2,539 adults without diabetes. Those who received tirzepatide lost about 15% to 21% over 72 weeks, depending on the study group; the group on a dummy shot lost about 3%.
A study called SCALE included 3,731 adults without diabetes. Those who received daily liraglutide lost about 8.4 kilograms over 56 weeks; the group on a dummy shot lost about 2.8 kilograms.
Next in the pathway
Keep the original records together
The reading list links to the FDA records and published study records used here.